Real-Time PCR Assays AmoyDx®

Seit 2015 bietet Zytomed Systems Produkte für die Real-Time PCR unserer Partnerfirma AmoyDx® an. Neben Kits zum Mutations-Nachweis sind Produkte für den Nachweis von Fusionstranskripten (ALK, ROS1, RET) und von Erregern (HPV) aus unterschiedlichem Ausgangsmaterial erhältlich. Die PCR-Assays sind kompatibel mit vielen gängigen Real-Time PCR-Geräten.

Vorteile der AmoyDx® Real-Time PCR Assays:

  • Hohe Sensitivität (Detektion von bis zu 1 % mutiertes Allel in wt-Hintergrund)
  • Ergebnisse innhalb von 90 Minuten
  • Externe und interne Kontrolle
  • Positiv- und Negativ-Kontrolle
  • Kompatibel mit vielen gängigen Real-Time PCR-Geräten


Die AmoyDx® Real-Time PCR Assays mit der neuen Super-ARMS™ Technologie (Super-Amplification Refractory Mutation System) wurden speziell für den Mutationsnachweis an ctDNA (circulating DNA) Proben entwickelt. Das neue Super-ARMS EGFR T790M Mutation Detection Kit erreicht im Vergleich zu den bisher auf dem Markt befindlichen Real-Time PCR Systemen eine erhöhte Sensitivität von bis zu 0,2 % Mutationsanteil in der wt-DNA beim T790M Nachweis. Ebenfalls neu ist das Super-ARMS™ EGFR Mutation Detection Kit. Dieses Kit ermöglicht den Nachweis von 42 Mutationen in den Exons 18 bis 21 des EGFR Gens an ctDNA mit einer Sensitivität von 0,2 – 0,8 % (T790M: 0,2 %).

Nachweis von Mutationen

Produkt Format Best-Nr. Menge Preis Status Info
BRAF V600 Mutations Detection Kit Bulk ADX-BR04 1 Kit (24 Tests) - CE/IVD
BRAF V600 Mutations Detection Kit - RG72 Bulk ADX-BR04-RG72 1 Kit (24 Tests) - CE/IVD
BRAF V600 Mutations Detection Kit V2 Bulk ADX-BR06-R 1 Kit (24 Tests) - RUO
C-KIT Mutation Detection Kit Bulk ADX-CK01-R 1 Kit (24 Tests) - RUO
EGFR 29 Mutations Detection Kit Bulk ADX-EG07 1 Kit (24 Tests) - CE/IVD
EGFR 29 Mutations Detection Kit pre-loaded ADX-EG01-A 1 Kit (10 Tests) - CE/IVD
EGFR 29 Mutations Detection Kit pre-loaded ADX-EG01-B 1 Kit (10 Tests) - CE/IVD
EGFR 29 Mutations Detection Kit pre-loaded ADX-EG01-C 1 Kit (10 Tests) - CE/IVD
EGFR 29 Mutations Detection Kit pre-loaded ADX-EG01-D 1 Kit (10 Tests) - CE/IVD
EGFR 29 Mutations Detection Kit - RG72 Bulk ADX-EG07-RG72 1 Kit (24 Tests) - CE/IVD
EGFR/ALK/ROS1 Mutations Detection Kit pre-loaded ADX-EAR01-A 1 Kit (8 Tests) - CE/IVD
EGFR/ALK/ROS1 Mutations Detection Kit pre-loaded ADX-EAR01-B 1 Kit (8 Tests) - CE/IVD
EGFR/ALK/ROS1 Mutations Detection Kit pre-loaded ADX-EAR01-D 1 Kit (8 Tests) - CE/IVD
HER2 Mutation Detection Kit Bulk ADX-HE01-R 1 Kit (12 Tests) - RUO
KRAS Mutation Detection Kit Bulk ADX-KR07 1 Kit (24 Tests) - CE/IVD
KRAS Mutation Detection Kit pre-loaded ADX-KR05-A 1 Kit (6 Tests) - CE/IVD
KRAS Mutation Detection Kit pre-loaded ADX-KR05-B 1 Kit (6 Tests) - CE/IVD
KRAS Mutation Detection Kit pre-loaded ADX-KR05-D 1 Kit (6 Tests) - CE/IVD
KRAS/NRAS/BRAF Mutations Detection Kit pre-loaded ADX-KN04-A 1 Kit (6 Tests) - CE/IVD
KRAS/NRAS/BRAF Mutations Detection Kit pre-loaded ADX-KN04-B 1 Kit (6 Tests) - CE/IVD
KRAS/NRAS/BRAF Mutations Detection Kit pre-loaded ADX-KN04-D 1 Kit (6 Tests) - CE/IVD
KRAS/NRAS Mutations Detection Kit Bulk ADX-KN05 1 Kit (24 Tests) - CE/IVD
KRAS/NRAS Mutations Detection Kit pre-loaded ADX-KN03-A 1 Kit (6 Tests) - CE/IVD
KRAS/NRAS Mutations Detection Kit pre-loaded ADX-KN03-D 1 Kit (6 Tests) - CE/IVD
MET Mutation Detection Kit Bulk ADX-ME02-A 1 Kit (24 Tests) - CE/IVD
MET Mutation Detection Kit Bulk ADX-ME02-D 1 Kit (24 Tests) - CE/IVD
MET Mutation Detection Kit Bulk ADX-ME02-J 1 Kit (24 Tests) - CE/IVD
Multi-Gene Mutations Detection Kit - ADX-LM01-A 1 Kit (6 Tests) - CE/IVD
Multi-Gene Mutations Detection Kit - ADX-LM01-B 1 Kit (6 Tests) - CE/IVD
Multi-Gene Mutations Detection Kit - ADX-LM01-D 1 Kit (6 Tests) - CE/IVD
Multi-Gene Mutations Detection Kit - ADX-LM01-J 1 Kit (6 Tests) - CE/IVD
NRAS Mutation Detection Kit Bulk ADX-NR01 1 Kit (24 Tests) - CE/IVD
NRAS Mutation Detection Kit pre-loaded ADX-NR02-A 1 Kit (8 Tests) - CE/IVD
NRAS Mutation Detection Kit pre-loaded ADX-NR02-B 1 Kit (8 Tests) - CE/IVD
NRAS Mutation Detection Kit pre-loaded ADX-NR02-D 1 Kit (8 Tests) - CE/IVD
Pan Lung Cancer PCR Panel Bulk ADX-LG02-R 1 Kit (12 Tests) - RUO -
Pan Lung Cancer PCR Panel pre-loaded ADX-LG01-JR 1 Kit (8 Tests) - RUO
PIK3CA Five Mutations Detection Kit Bulk ADX-PI01 1 Kit (24 Tests) - CE/IVD
PIK3CA Five Mutations Detection Kit Bulk ADX-PI01-RG72-R 1 Kit (12 Tests) - RUO
TERT/HRAS Mutations Detection Kit - ADX-TH01-BR 1 Kit (24 Tests) - RUO -
TERT/HRAS Mutations Detection Kit - ADX-TH01-DR 1 Kit (24 Tests) - RUO -

Super-ARMS Kits: Nachweis von Mutationen an cfDNA

Produkt Format Best-Nr. Menge Preis Status Info
Super-ARMS EGFR C797S Mutation Detection Kit Bulk ADX-EG20-R 1 Kit (12 Tests) - RUO -
Super-ARMS EGFR Color Compensation Kit - 8.01.20218X012B 1 Kit (12 Tests) - RUO
Super-ARMS EGFR Mutation Detection Kit Bulk ADX-EG21 1 Kit (12 Tests) - CE/IVD
Super-ARMS EGFR Mutation Detection Kit - RG36 - ADX-EG21-RG36-R 1 Kit (12 Tests) - RUO
Super-ARMS EGFR T790M Mutation Detection Kit Bulk ADX-EG12 1 Kit (24 Tests) - CE/IVD
Super-ARMS KRAS/NRAS/BRAF Mutations Detection Kit Bulk ADX-KN06 1 Kit (24 Tests) - CE/IVD

Erregernachweise

Produkt Format Best-Nr. Menge Preis Status Info
High-risk Human Papillomavirus (HPV) Detection Kit Bulk ADX-HP03 1 Kit (48 Tests) - CE/IVD
HPV 6/11/16/18 Detection Kit Bulk ADX-HP02 1 Kit (48 Tests) - CE/IVD
Human Papillomavirus (HPV) Genotyping Detection Kit Bulk ADX-HP04 1 Kit (48 Tests) - CE/IVD -
Human Papillomavirus (HPV) Genotyping Detection Kit pre-loaded ADX-HP01-D 1 Kit (48 Tests) - CE/IVD

Nachweis von Fusionstranskripten

Produkt Format Best-Nr. Menge Preis Status Info
ALK Gene Fusions and ROS1 Gene Fusions Detection Kit pre-loaded ADX-AR01-A 1 Kit (8 Tests) - CE/IVD
ALK Gene Fusions and ROS1 Gene Fusions Detection Kit pre-loaded ADX-AR01-B 1 Kit (8 Tests) - CE/IVD
ALK Gene Fusions and ROS1 Gene Fusions Detection Kit pre-loaded ADX-AR01-D 1 Kit (8 Tests) - CE/IVD
EGFR/ALK/ROS1 Mutations Detection Kit pre-loaded ADX-EAR01-A 1 Kit (8 Tests) - CE/IVD
EGFR/ALK/ROS1 Mutations Detection Kit pre-loaded ADX-EAR01-B 1 Kit (8 Tests) - CE/IVD
EGFR/ALK/ROS1 Mutations Detection Kit pre-loaded ADX-EAR01-D 1 Kit (8 Tests) - CE/IVD
EML4-ALK Fusion Gene Detection Kit Bulk ADX-AE01 1 Kit (24 Tests) - CE/IVD
EML4-ALK Fusion Gene Detection Kit pre-loaded ADX-AE02-A 1 Kit (12 Tests) - CE/IVD
EML4-ALK Fusion Gene Detection Kit pre-loaded ADX-AE02-B 1 Kit (12 Tests) - CE/IVD
Multi-Gene Mutations Detection Kit - ADX-LM01-A 1 Kit (6 Tests) - CE/IVD
Multi-Gene Mutations Detection Kit - ADX-LM01-B 1 Kit (6 Tests) - CE/IVD
Multi-Gene Mutations Detection Kit - ADX-LM01-D 1 Kit (6 Tests) - CE/IVD
Multi-Gene Mutations Detection Kit - ADX-LM01-J 1 Kit (6 Tests) - CE/IVD
NTRK Gene Fusions Detection Kit Bulk ADX-NT01-R 1 Kit (24 Tests) - RUO
Pan Lung Cancer PCR Panel Bulk ADX-LG02-R 1 Kit (12 Tests) - RUO -
Pan Lung Cancer PCR Panel pre-loaded ADX-LG01-JR 1 Kit (8 Tests) - RUO
RET Gene Fusions Detection Kit Bulk ADX-RE05 1 Kit (12 Tests) - CE/IVD
ROS1 Gene Fusions Detection Kit Bulk ADX-RO03 1 Kit (12 Tests) - CE/IVD
ROS1 Gene Fusions Detection Kit pre-loaded ADX-RO02-A 1 Kit (12 Tests) - CE/IVD
ROS1 Gene Fusions Detection Kit pre-loaded ADX-RO02-B 1 Kit (12 Tests) - CE/IVD

AmoyDx® DNA/RNA Extraction Kits

Produkt Format Best-Nr. Menge Preis Status Info
Blood DNA Kit - ADX-BL01-R 1 Kit (36 Tests) - RUO
Circulating DNA Kit - ADX-BL03 1 Kit (24 Tests) - CE/IVD
FFPE DNA Kit - ADX-FF01 1 Kit (36 Tests) - CE/IVD
FFPE DNA/RNA Kit - ADX-FF03 1 Kit (36 Tests) - CE/IVD
FFPE RNA Kit - ADX-FF04 1 Kit (36 Tests) - CE/IVD
Tissue DNA Kit - ADX-TI01-R 1 Kit (36 Tests) - RUO
Tissue DNA/RNA Kit - ADX-TI03-R 1 Kit (36 Tests) - RUO
Tissue RNA Kit - ADX-TI02-R 1 Kit (36 Tests) - RUO

zurück zu Molekularpathologie